Extra-Intestinal Manifestations of Familial Adenomatous Polyposis
نویسندگان
چکیده
منابع مشابه
Extra-colonic manifestations of familial adenomatous polyposis.
Familial adenomatous polyposis (FAP) is a genetic disease created by an abnormality of chromosome number five resulting in a generalized cellular growth disorder. The growth abnormality created by the genetic defect dictates the development of benign and malignant lesions in different organs of the body. Even the term familial adenomatous polyposis does not fully describe the defect because les...
متن کامل[Intestinal and extraintestinal manifestations in familial adenomatous polyposis].
Familijarna adenomatozna polipoza (FAP) je autozomno dominantni polipozni sindrom, odgovoran za pojavu oko 1% svih kolorektalnih karcinoma (CRC) . Ovaj sindrom se ispoljava kod 1/5 000 do 1/17 000 živorođene dece 2, 3 sa stopom penetracije od preko 90% . Zahvata podjednako oba pola i sve geografske lokalitete . Obolele osobe razvijaju 100−5 000 adenoma (prosečan broj adenoma > 1 000) tubularne ...
متن کاملextracolonic manifestations in familial adenomatous polyposis
introduction: due to the whole network of polyposis registers worldwide and early prophylactic treatment, survival of familial adenomatosis (fap) patients is improved. extracolonic manifestations are remarkable feature of fap. two extracolonic manifestations (duodenal adenomatosis, leading duodenal cancer and desmoid tumours) play a very important role in the reasons of death in polyposis popul...
متن کاملSurgical management of the duodenal manifestations of familial adenomatous polyposis.
BACKGROUND Duodenal adenomas develop in patients with familial adenomatous polyposis, incurring a risk of carcinoma. When this risk is high, surgery is indicated. The choice of surgical treatment can be difficult as evidence-based data are lacking. METHODS This is a systematic review of the literature on the non-medical management of duodenal lesions arising in the setting of familial adenoma...
متن کاملExtracolonic manifestations of familial adenomatous polyposis after proctocolectomy.
HYPOTHESIS Extracolonic manifestations have a major effect on the morbidity and mortality of patients with familial adenomatous polyposis following proctocolectomy. DESIGN Case review study. SETTING Colorectal unit, university-affiliated hospital. PATIENTS Fifty patients (25 males and 25 females) with familial adenomatous polyposis WHO underwent proctocolectomy between January 1988 and Oc...
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ژورنال
عنوان ژورنال: Annals of Surgical Oncology
سال: 2008
ISSN: 1068-9265,1534-4681
DOI: 10.1245/s10434-008-9981-3